PCA3 NONCODING RNA IS INVOLVED IN THE CONTROL OF PROSTATE-CANCER CELL SURVIVAL AND MODULATES ANDROGEN RECEPTOR SIGNALING

PCA3 noncoding RNA is involved in the control of prostate-cancer cell survival and modulates androgen receptor signaling

Abstract Background PCA3 is a non-coding RNA (ncRNA) that is highly expressed in prostate cancer (PCa) cells, but its functional role is unknown.To investigate its putative function in PCa biology, we used gene expression knockdown by small interference RNA, and also analyzed its involvement in androgen receptor (AR) signaling.Methods LNCaP and PC3

read more


Effect of feeding goats with leguminous shrubs (Chamaecytisus proliferus ssp. Palmensis and Bituminaria bituminosa) on milk and cheese properties

Physical-chemical parameters, fatty acid profile and sensorial characteristics of experimental Palmero cheese from 2 equivalent groups of 20 Palmero goats fed 2 diets with different long fibre to concentrate ratio (65/35) or (35/65) with leguminous autochthonous forages (tagasaste and tedera) (DF) or wheat straw (DC) respectively as long fibre part

read more


Analysis of fish viral disease epidemic situation worldwide

The epidemic situation on aquaculture diseases worldwide is of relevance for our country as this information makes it possible to imagine Wet a risk of infection spread among countries and to determine effectiveness of necessary measures aimed at prevention of these diseases spread in territories of neighboring and other countries.The epidemiologic

read more